Protein Structure: From Primary Sequence to Quaternary Complexity

Explore the complete hierarchy of protein structure — from primary amino acid sequence to complex tertiary and quaternary folding. Learn about peptide bonds, alpha helices, beta sheets, motifs, domains, and how structure determines function in biology.

BIOTECHNOLOGY

Dr. Mainak Mukhopadhyay

11/5/20251 min read

Structure and Hydrogen Bonding Pattern of an α-Helix

en:User:Bikadi, CC BY-SA 3.0 <http://creativecommons.org/licenses/by-sa/3.0/>, via Wikimedia Commons

Beta sheet bonding antiparallel

Fvasconcellos, Public domain, via Wikimedia Commons

Beta sheet bonding parallel

Tertiary Structure of a Protein

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Quaternary Structure of a Protein

Zephyris at the English-language Wikipedia, CC BY-SA 3.0 <http://creativecommons.org/licenses/by-sa/3.0/>, via Wikimedia Commons